Brief Reviews: Hemodynamic Theories of Atherogenesis
نویسندگان
چکیده
منابع مشابه
Commentary Vascular Endothelium, Hemodynamic Forces, and Atherogenesis
Intimal lipid accumulation, hyperplasia, and scarring are stigmata of atherosclerotic vascular disease, whose major complications—myocardial and cerebral ischemia and infarction—continue to be major health problems in developed nations. This insidiously progressive disease typically spans decades, but can reach a clinical horizon in a matter of minutes due to critical changes in a given atheros...
متن کاملBrief reviews
Dr. Weintraub et al. has written a comprehensive review of cognitive profiles among aging and dementias, comparing them to the neuropsychological deficits seen in Alzheimer’s disease (AD). The authors described the neuropsychological findings regarding episodic memory, language and semantic knowledge, executive functions, working memory and attention; and visuospatial abilities. The article hig...
متن کاملEndothelial glucocorticoid receptor suppresses atherogenesis--brief report.
OBJECTIVE The purpose of this study was to determine the role of the endothelial glucocorticoid receptor in the pathogenesis of atherosclerosis. APPROACH AND RESULTS Control mice and mice lacking the endothelial glucocorticoid receptor were bred onto an Apoe knockout background and subjected to high-fat diet feeding for 12 weeks. Assessment of body weight and total cholesterol and triglycerid...
متن کاملBRIEF REVIEWS Stimulus-Secretion Coupling of Renin Role of Hemodynamic and Other Factors
IT IS generally agreed that three intrarenal receptors control renin secretion. The macula densa receptor responds to some yet unknown function of the fluid passing the distal nephron (Thurau, 1964; Vander, 1967; Kotchen et al., 1978). The neurogenic receptor, which presumably is on the juxtaglomerular cell membrane, stimulates renin secretion by a /?-adrenergic mechanism and inhibits by an a m...
متن کاملHemodynamic shear stresses in mouse aortas: implications for atherogenesis.
OBJECTIVE The hemodynamic environment is a determinant of susceptibility to atherosclerosis in the vasculature. Although mouse models are commonly used in atherosclerosis studies, little is known about local variations in wall shear stress (WSS) in the mouse and whether the levels of WSS are comparable to those in humans. The objective of this study was to determine WSS values in the mouse aort...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Circulation Research
سال: 1973
ISSN: 0009-7330,1524-4571
DOI: 10.1161/01.res.33.3.259